Spontaneous penoscrotal bleeding in haemophilia A.
نویسندگان
چکیده
To cite: Siddiqui SA, Tomar V. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016217596 DESCRIPTION A boy aged 3 years presented to the emergency department with sudden onset of painless penoscrotal swelling and ecchymosis of 2 days. There was no history of trauma or similar presentation before this episode. No family history of bleeding disorder was present. On examination, his vitals were stable. Temperature of the scrotum and penis was normal. There was penoscrotal oedema and ecchymosis with loss of scrotal rugosities and normal shape of penis (figure 1). His blood investigations were unremarkable except for prolonged aPTT. Factor assay was performed which came out to be moderate factor VIII deficiency (3.4 IU/dL). The patient was started on intravenous recombinant factor VIII as per World Federation of Haemophilia (WFH) protocol. Bleeding was confirmed on high-resolution ultrasonography scan of the scrotum. The patient had an uneventful recovery in a week.
منابع مشابه
Prevention of spontaneous bleeding in dogs with haemophilia A and haemophilia B.
Dogs with haemophilia A or haemophilia B exhibit spontaneous bleeding comparable with the spontaneous bleeding phenotype that occurs in humans with severe haemophilia. The phenotypic and genotypic characteristics of haemophilic dogs have been well-described, and such dogs are suitable for testing prophylactic protein replacement therapy and gene transfer strategies. In dogs with haemophilia, lo...
متن کاملLack of seasonal variation in bleeding and patient-assessed pain patterns in patients with haemophilia B receiving on-demand therapy
Spontaneous haemorrhage in patients with haemophilia is generally considered to occur randomly and without a predictable temporal or seasonal pattern; however, there is a lack of evidence in the literature on the effects of weather, temperature and atmosphere on bleeding episodes. This post hoc analysis of a multicentre, open-label crossover study examined the influence of seasonality on bleedi...
متن کاملTreatment of haemophilia in the elderly.
UNLABELLED Treatment of elderly patients with haemophilia is an upcoming challenge in haemophilia care. We included patients with haemophilia A older than 60 years of age, who visited our haemophilia centre between 2006 and 2008. We conducted a retrospective study focussing on the patients' co-morbidities as well as changes in their bleeding patterns between 2003 and 2008. RESULTS There is a ...
متن کاملRare diseases treated by plasma proteins
When plasma is separated or recovered from a blood donation or when plasma is collected by plasmapheresis the end result is not just a fluid which can be used in the treatment of many medical conditions but a raw material which can be used for the production of specific life saving or life enhancing medications for a variety of conditions. These conditions include Haemophilia A and Haemophilia ...
متن کاملManagement of pregnancy in a patient with severe haemophilia A.
Haemophilia A is a bleeding disorder that has a spectrum of manifestations ranging from persistent bleeding after minor trauma to spontaneous haemorrhage. As an X-linked disease, it has a rare occurrence in females. We report a case of a pregnant patient with severe haemophilia A, who received epidural analgesia during labour. The prepartum, intrapartum and postpartum care of a patient with suc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- BMJ case reports
دوره 2016 شماره
صفحات -
تاریخ انتشار 2016